A New Spin on Planar Cell Polarity

نویسندگان

  • Patricio Olguin
  • Marek Mlodzik
چکیده

The generation of planar cell polarity (PCP) and tissue shape during morphogenesis is tightly linked, but it is not clear how. Aigouy et al. (2010) now show in the developing Drosophila wing that PCP initially has a radial orientation that becomes realigned to the proximal-distal axis of organ shape by mechanical forces and cell rearrangements mediated by Dachsous.

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عنوان ژورنال:
  • Cell

دوره 142  شماره 

صفحات  -

تاریخ انتشار 2010